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Weinberg, and R.T

10.1016/j.neuropharm.2012.02.015 Neuropharmacology 12 BaraczS

Among others, actions of IGF-I on cardiac stem cells include antioxidant effects, upregulation of telomerase activity, a delay in replicative senescence[288], and migration and homing of cardiac stem cells facilitating neovascularization in damaged hearts[287]

Cross-sectional studies also linked abnormal TC, HDL, LDL, and TG levels to DED progression, potentially through impaired tear film stability and meibomian gland dysfunction (MGD) [49]

This has implications for the genetic diagnosis of THAP1 dystonia and supports the use of broader strategies like targeted next generation or whole exome sequencing in this population