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Hayne D, Vaizey CJ, Boulos PB

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Petersburg Institute of Bioregulation and Gerontology in the late 1980s and 1990s as a synthetic analogue of the natural pineal-gland-extract complex epithalamin

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Mechanistically, the CD73/A2AR signaling cascade coordinates the de novo synthesis and consumption of GSH with GSSG accumulation and concomitant mitochondrial lipid peroxidation, which links potentially to PKA/E2F1dependent fine-tuning of the ratio of GSR to GPX4

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10.1001/archopht.118.5.666 Arch

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