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By altering the activity of enzymes involved in lipid metabolism, this variation may have an impact on hepatic inflammation[59]

To view a copy of this licence, visit About this article Cite this article Reis Filho, J.M., de Sousa Marques, I.L., Kangussu, L.M

Preclinical validation of novel drug candidates for the treatment of NASH requires a translational animal model that should recapitulate these hallmarks of the human disease