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Structural alignment of the AL domain (residues 1270) between substrate-bound (s-state) and product-bound (p-state) hCTPS1 revealed an RMSD of 1.267 , with conformational differences localized to the Arch region (residues 4567) and Loop183194

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CD-8depleted donor lymphocyte infusion (DLI) for the treatment of CML relapse after allogeneic transplant: long-term follow-up and factors predicting of outcome